The Michael J. Fox Foundation will award one-to-two-year grants for alpha-synuclein research to advance understanding of alpha-synuclein biology and accelerate therapeutic approaches.
This program seeks proposals for research studying:
- The role of alpha-synuclein and modified forms in health and disease
- The relationship between alpha-synuclein structure and physiological functions
- Novel therapeutic approaches targeting intracellular alpha-synuclein or related pathways
A pathological hallmark of Parkinson’s and other neurodegenerative disorders, alpha-synuclein accumulation into Lewy bodies is thought to play a major role in the onset and/or progression of disease. Clinical trials are ongoing for several potential treatments targeting extracellular alpha-synuclein. MJFF will support projects aimed at altering intracellular alpha-synuclein in order to broaden the scope of therapeutic approaches.
For more information, please visit: https://www.michaeljfox.org/research/grant-detail.php?id=34&et_cid=10623...
- Biochemistry/Biophysics
- Clinical Science
- Molecular Biology/Cell Biology
- Neuroscience
- Faculty
- Junior Faculty