The Molecular Biophysics Core, situated at 1300 York in Rooms C507/C511, is designed to support both novice and advanced users in the purification and characterization of macromolecules, streamlining these processes efficiently. The facility is outfitted with a variety of instruments and offers extensive services to facilitate the functional and biophysical characterization of proteins, liposomes, proteo-liposomes, and other macromolecules.
As shown below, the facility offers a variety of instruments for independent use along with services that are offered to support various research needs.
Services
- Changes in lipid bilayer properties per condition.
- Lipid vesicle preparation
- Protein purification consultation
- Expression vector design
Equipment
- Circular Dichroism (4-hour block)
- FSEC (4-hour block)
- Low and standard Volume ITC (4 hour block)
- Affinity Auto-ITC (use/day)
- Dynamic Light Scattering (per hour)
- Spectrofluorometer (per day)
- Nanion SURFE2R (per hour)
- Gramicidin electrophysiology set-up (per day)
- Refeyn Mass Photometer (per hour)
- NanoTemper Tycho - Differential scanning fluorometry (per hour)
- NanoTemper Monolith – Microscale electrophoresis (per hour)
- AKTA Pure (per day)
- SX20 stopped-flow (per hour)
- SX20 stopped-flow (with Vesicle sample prep)
More Information
For more information about services and pricing, to register as a user of the core, to schedule time on the instruments, and/or to arrange for training, please go to the our iLab page.
Contact Information
Core Manager: Radda Rusinova Ph.D
Email: rar2021@med.cornell.edu
Phone: 212-746-9416