Metabolic Phenotyping

The Metabolic Phenotyping Center (MPC) offers an extensive range of services for comprehensive metabolic phenotyping in the mouse and bioenergetics of live cells.

Ambient temperature and light-controlled Promethion metabolic cages assess oxygen consumption and carbon dioxide production (energy expenditure) as well as activity, body weight, and food and water intake in real-time. An additional ambient temperature and light-controlled incubator are available for temperature exposure studies. Lean and fat mass can be quantified via EchoMRI, radiated heat with FLIR infrared thermography, and food absorption efficiency using oxygen bomb calorimetry. Complementing these analyses, whole-body glucose metabolism can be assessed via glucose, insulin, and pyruvate tolerance tests.

Oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) can be measured in live cells and isolated mitochondria using Agilent Seahorse XFe96 and XFe24 Analyzers. Read more about the Metabolic Phenotyping Center (MPC).

More Information

Read  more about the Metabolic Phenotyping Center (MPC).

Contact Information

Core Contact: Hayley T Nicholls Krisko & Sarah (Grey) McAlaine

Email: mpcenter@med.cornell.edu

Phone: 646-962-674