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Data and Safety Monitoring Committee (DSMC)


The Weill Cornell Medicine Data and Safety Monitoring Committee (WCM DSMC) is an independent committee within the institution that is available to the research community to act as a monitoring entity for clinical trials. It performs a regular review of cumulative data to evaluate research subject safety, rates of accrual, and efficacy of experimental intervention.  Based on its review, the WCM DSMC provides investigators with recommendations for protocol modification, continuation or termination.  The intensity ad frequency at which the WCM DSMC monitors a study is commensurate with the study's risks and needs.  

 If you are unsure of whether your study needs WCM DSMC oversight, contact for assistance.


Q: How do I request WCM DSMC oversight?

A: WCM DSMC oversight can be requested via the following: 

1) The Human Subjects System by indicating the appropriate responses in the Intake Form or Initial IRB application.   

2) Via a direct email request submitted to  

For more details, please refer to the following information page: Make a Submission


Meeting dates and their associated deadlines for the WCM DSMC are provided below.  

Starting September 16, 2020, the WCM DSMC will split into the General and Cancer subcommittees.  These will meet at 2:00 PM, every third Wednesday on alternating months, starting with the Cancer subcommittee.  

CancerWednesday, September 16, 2020Wednesday, August 26, 2020
GeneralWednesday, October 21, 2020Wednesday, September 30, 2020
CancerWednesday, November 18, 2020Wednesday, October 28, 2020
GeneralWednesday, December 16, 2020Wednesday, November 25, 2020
CancerWednesday, January 20, 2021Wednesday, December 30, 2020
General Wednesday, February 17, 2021Wednesday, January 27, 2021
CancerWednesday, March 17, 2021Wednesday, February 24, 2021
GeneralWednesday, April 21, 2021Wednesday, March 31, 2021
CancerWednesday, May 19, 2021Wednesday, April 28, 2021
GeneralWednesday, June 16, 2021Wednesday, May 26, 2021
CancerWednesday, July 21, 2021Wednesday, June 30, 2021
GeneralWednesday, August 18, 2021Wednesday, July 28, 2021

Past Announcements: 

10/8/2020: The WCM DSMC has been updated to version 17 August 2020.  This SOP is in effect as of October 5, 2020.  

Office Contacts

Alavy Sos
Director, Human Subjects Protections Program
Aileen Orpilla
Research Compliance Specialist
Lauren Blumberg
Assistant Director, Regulatory Compliance